The data presented in this paper is generated from SLS and DLS experiments that monitored the solution behavior of rAAV capsids with and without DNA. The comparison and superimposition of SLS and DLS scattering profiles provides insights into the differential colloidal stability of the full and empty species, as well as a dynamic quantification of...Read More
These rAAV capsid stability experiments investigated and monitored the solution behavior of full and empty capsids under thermal stress using ARGEN. ARGEN is uniquely suitable for in situ and real-time characterization of solution stability of larger species such as rAAVs and LNP-RNA complexes. This case study demonstrates ARGEN's ability to elucidate differences in full and...Read More
