Rapid Analysis of Protein Formulation Stability ARGEN, by Fluence Analytics, adds another powerful tool to the protein scientist’s arsenal. ARGEN is a light scattering instrument with 16 independent sample cells that can test for protein aggregation while stressing samples under multiple conditions including chemical, mechanical and thermal…all in real time and accelerating protein formulation stability!...Read More
Realtime Monitoring for Polymerization Reactions ACOMP is a smart manufacturing system that provides realtime monitoring of polymerizations during production. This automated monitoring solution produces real-time insight into reaction kinetics and polymer properties such as residual monomer, monomer conversion, polymer composition, molecular weight, and intrinsic viscosity. ACOMP enables optimized process control, resulting in increased polymer yield,...Read More
Determine the Stability of Biologics This peer review article from American Pharmaceutical Review describes new tools for determining the stability of biologics, including ARGEN by Fluence Analytics, that not only have low sample requirements but also generate precise and reproducible data to effectively implement an advanced design of experiments approach. This article uses a real case...Read More
Fluence Analytics collaborated with its academic research partner Tulane PolyRMC on a peer review publication in Macromolecular Reaction Engineering. An automatic molecular weight controller is used in semi-batch reactions to produce multimodal polymers that contain distinct subpopulations with different molecular weight distributions (MWD). While blending polymers with different MWD is frequently used to make products from...Read More
PepTalk, one of the largest annual conferences for protein researchers in the world, will take place from January 8-12, 2018 at the Hilton San Diego Bayfront. Fluence Analytics is attending the 17th annual conference and will showcase ARGEN at exhibition booth number 315. The booth will feature an ARGEN system with software demos, and members of...Read More
Launch of New Demo Program Allows Companies to Experience ACOMP’s Powerful Data First-hand (New Orleans, LA, U.S.) ‒ Fluence Analytics, a manufacturer of industrial and laboratory monitoring systems, today announced the release of its third-generation ACOMP product. ACOMP is an automated smart manufacturing system that continuously analyzes polymers during production and produces realtime insights into reaction kinetics and...Read More
Fluence Analytics and its academic research partner Tulane PolyRMC collaborated on a peer review article for Macromolecules which discusses using ACOMP to automatically control polymer molecular weight during synthesis. The continuous record of monomer and polymer concentrations, Cm and Cp, and cumulative weight-average mass, Mw, furnished by automatic continuous online monitoring of polymerization reactions (ACOMP) has been harnessed...Read More
In these experiments, ARGEN was used to characterize the thermal and chemical stability of a monoclonal antibody and subsequently establish quantitative and qualitative properties such as pH and temperature dependence on aggregation kinetics. Additionally, SEC elution profiles were superimposed onto Mw/Mo output, providing a robust comparison and identification of the stability landscape for the mAb....Read More
