Recent research on stress factors in monoclonal antibody development underscores the critical need for robust control strategies in monoclonal antibody drug substance production, focusing on the risks posed by various stress conditions during manufacturing. These stressors can lead to protein modifications, impacting both patient safety and product quality. ARGEN, by Yokogawa Fluence Analytics, is a...Read More
The academic research partner of Yokogawa Fluence Analytics, Tulane PolyRMC, partnered with Spark Therapeutics on a new peer-reviewed article in Biomacromolecules that highlights the degradation of adeno-associated virus (AAV) under moderate thermal stress (30−53°C) and in physiological solution (pH7.2, 180 mM NaCl). Read More
Characterizing colloidal stability is central to developing safe and efficacious protein-based therapeutics. To be viable, the target biotherapeutic must remain stable during production, storage, and patient delivery. The most insightful and successful techniques for monitoring and characterizing colloidal stability involve in-situ and real time analysis under modelled stress conditions. This permits the investigation of solution...Read More
This article provides a high-level comparison of light scattering techniques, including similarities and differences between them in biopharma applications.Read More
The 2024 AAPS National Biotechnology Conference will take place in San Francisco, CA from Monday, May 13 through Thursday, May 16. Yokogawa Fluence Analytics' Life Science Product Manager, Dr. Jason Allison, will present during the poster sessions on Tuesday and Wednesday. Dr. Allison's poster is titled Static Light Scattering Signatures Used to Identify and Minimize Aggregation During...Read More
Scientists involved in biopharmaceutical research face several key challenges during the development of therapeutic proteins, peptides and RNA. This article explores key challenges and innovations in biopharmaceutical formulation development that help scientists overcome those challenges.Read More
ARGEN is a robust platform that can expand biopolymer formulation development efforts via novel data sets. The precision instrument addresses key challenges in biopolymer research by offering in-situ, real-time stability monitoring, manufacturing stress modelling, shelf-life determination, and rapid parallel analysis, leading to more efficient and effective formulation development.Read More
The food and beverage industry faces a myriad of challenges in research and development, primarily centered around ensuring the stability, quality, and safety of products across different environmental conditions and production scales. These challenges include the complexities of ingredient behavior under processing stress and the critical need for consistency across batches. Innovations in analytical technologies,...Read More
Fluence Analytics, a leader in continuous analytics and process control solutions for the polymer and biopharmaceutical industries, was named as one of the "Best Places to Work" in Houston in 2023 by Built In. In addition to the Best Place to Work recognition, Fluence Analytics was also named as one of the "50 Best Startups...Read More
