Tag

biopharmaceutical stability

Therapeutic Antibody and RNA Development

For formulation scientists working on cutting-edge research involving therapeutic antibody and RNA development, integrating ARGEN into your workflow can provide a significant competitive advantage. By leveraging ARGEN's real-time stability monitoring and stress modeling capabilities, you can optimize your formulations for both stability and efficacy, reducing the risk of late-stage failures and ensuring that your therapeutic...
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New Technique to Monitor DNA Release and Capsid Protein Stability

This dynamic webinar offers insights into characterizing the stability of an engineered adeno-associated virus (AAV) serotype under moderate thermal stress and physiological solution conditions using light scattering measurements. This webinar highlights experiments that investigated and characterized the effects of thermally-induced perturbations on DNA ejection from a proprietary AAV vector. The experiments were conducted at three...
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Impact of ARGEN on Peptide Stability

In the rapidly evolving world of biopharmaceutical research, the search to optimize formulation development efforts and understand peptide stability has taken center stage. With a myriad of applications ranging from the treatment of diseases to novel delivery systems, the potential of peptides is vast.  
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Antibody Stability in Biopharmaceutical Research

In the high-stakes realm of biopharmaceutical research and development, understanding antibody stability is very important. Antibody stability is a multi-faceted concern that includes aspects of aggregation, degradation, and conformational integrity. Each of these potential problems can negatively impact antibody stability and the performance and manufacturability of biotherapeutics.
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Advancing Custom Peptide and Oligonucleotide Development

In the realm of biopharmaceuticals, custom peptide and oligonucleotide development has opened new horizons for targeted therapeutic interventions. However, the success of peptide and oligonucleotide development hinges significantly on a comprehensive understanding of their stability. However, biopharma teams using ARGEN can access real-time stability insights as they develop peptide, oligonucleotide, and protein-based therapeutics. 
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Enhancing Monoclonal Antibody Development

Recent research on stress factors in monoclonal antibody development underscores the critical need for robust control strategies in monoclonal antibody drug substance production, focusing on the risks posed by various stress conditions during manufacturing. These stressors can lead to protein modifications, impacting both patient safety and product quality. ARGEN, by Yokogawa Fluence Analytics, is a...
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Mastering Colloidal Stability

Characterizing colloidal stability is central to developing safe and efficacious protein-based therapeutics. To be viable, the target biotherapeutic must remain stable during production, storage, and patient delivery. The most insightful and successful techniques for monitoring and characterizing colloidal stability involve in-situ and real time analysis under modelled stress conditions. This permits the investigation of solution...
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Comparison of Light Scattering Techniques

This article provides a high-level comparison of light scattering techniques, including similarities and differences between them in biopharma applications.
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Improving Efficiency & Data Accuracy in Biopharmaceutical Stability Testing

This article discusses how ARGEN is leading the way in improving efficiency and data accuracy in biopharmaceutical stability testing.
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Key Challenges and Innovations in Biopharmaceutical Formulation Development

Scientists involved in biopharmaceutical research face several key challenges during the development of therapeutic proteins, peptides and RNA. This article explores key challenges and innovations in biopharmaceutical formulation development that help scientists overcome those challenges.
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