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real-time Technology
ARGEN

Comparing Protein Stability: ARGEN Application Note 001

Comparing the Stability of Protein Formulations with ARGEN   Abstract Biopharmaceutical companies isolate many types of proteins for use in experimental and therapeutic medicines. Unfortunately, when  removed from their native environments, proteins become less stable. Unstable proteins are more prone to degradation from the primary stress mechanisms: mechanical and thermal (from manufacturing, storage and transport) and...
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Webinar: Introduction to ARGEN

Protein Formulation Stability – Rapid Analysis ARGEN, by Fluence Analytics, adds another powerful tool to the protein scientist’s arsenal. ARGEN is a light scattering instrument with 16 independent sample cells that can test for protein aggregation while stressing samples under multiple conditions including chemical, mechanical and thermal…all in real time and accelerating protein formulation stability!...
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Webinar: Introduction to ACOMP

 Realtime Monitoring for Polymerization Reactions ACOMP is a smart manufacturing system that provides realtime monitoring of polymerizations during production. This automated monitoring solution produces realtime insight about reaction kinetics and polymer properties such as residual monomer, monomer conversion, polymer composition, molecular weight and intrinsic viscosity. ACOMP enables optimized process control, resulting in increased polymer yield,...
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Fluence Analytics to exhibit and present new developments in use of light scattering to determine aggregation rates at PepTalk 2018

PepTalk, one of the largest annual conferences for protein researchers in the world, will take place from January 8-12, 2018 at the Hilton San Diego Bayfront. Fluence Analytics is attending the 17th annual conference and will showcase ARGEN at exhibition booth number 315. The booth will feature an ARGEN system with software demos, and members of...
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ACOMP

Fluence Analytics Releases Third-Generation ACOMP

Launch of New Demo Program Allows Companies to Experience ACOMP’s Powerful Data First-hand (New Orleans, LA, U.S.) ‒ Fluence Analytics, a manufacturer of industrial and laboratory monitoring systems, today announced the release of its third-generation ACOMP product. ACOMP is an automated smart manufacturing system that continuously analyzes polymers during production and produces realtime insights into reaction kinetics and...
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ARGEN_PEGS Boston 2018

Generating Aggregation Rates: ARGEN Technical Note 002

Generating Aggregation Rates to Determine Stability of Monoclonal Antibodies Background Static light scattering is widely used to measure the molar masses of molecules, particles and their aggregates under various solution conditions and compositions1. The ARGEN instrument has the capability to run 16 independent light scattering experiments simultaneously. It can monitor the change in both absolute...
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ARGEN_PEGS Boston 2018

Introduction to ARGEN: Technical Note 001

ARGEN: The Aggregation Rate GENerator that monitors protein and polymer stability Summary Fluence Analytics ARGEN platform continuously measures the light scattering from 16 independent solutions to assess the pharmaceutical stability of therapeutic proteins and natural polymers. ARGEN applies temperature and stirring stressors independently to each of the 16 sample cells, replicating the conditions of and...
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ACOMP

Monitoring the polymerization of PVP: ACOMP Application Note 001

Monitoring the effect of initiator concentration on molecular weight and intrinsic viscosity of polyvinyl pyrrolidone (PVP) using ACOMP Abstract Automatic Continuous Online Monitoring of Polymerization Reactions (ACOMP) was used to monitor the free radical polymerization of polyvinyl pyrrolidone (PVP) throughout the reaction. Two batch reactions were run at 1.5% and 2.5% initiator concentration to monitor...
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ACOMP

Introduction to ACOMP: Technical Note 001

ACOMP: The Automated System that allows Continuous Realtime Monitoring of Polymerization Reactions Abstract ​ ACOMP (Automatic Continuous Online Monitoring of Polymerization Reactions) is a patented product from Fluence Analytics that continuously monitors and characterizes polymers during polymerization or post-polymerization processing steps of laboratory or industrial scale polymerization reactions. Beyond allowing the user to monitor polymerizations...
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ARGEN_PEGS Boston 2018

Fluence Analytics Announces ARGEN Product Launch

New Instrument Continuously Analyzes Protein and Natural Polymer Aggregation (New Orleans, LA, U.S.) ‒ Fluence Analytics, a manufacturer of realtime, industrial and laboratory monitoring systems, today announced the launch of ARGEN, a patented protein and polymer stability monitoring product. By utilizing continuous light scattering measurements, ARGEN yields a unique information stream which reduces discovery and...
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